Vaccine-Associated Disease Enhancement (VADE): Exploring true incidence of VADE on vaccinated individuals.

Résumé du livre

Vaccine-Associated Disease Enhancement (VADE): Exploring true incidence of VADE on vaccinated individuals.

       The COVID-19 pandemic has affected 109 million people, causing 2.4 million deaths worldwide to date

      The COVID-19 pandemic has entered a new phase with the roll-out of several vaccines worldwide at an accelerated phase.

      The occurrence of a more severe presentation of COVID-19 after vaccination may affect policymakers’ decision-making and vaccine uptake by the public.

       Vaccine-associated disease enhancement (VADE) is the modified presentation of infections in individuals after having received a prior vaccination.

       Currently, little is known about the potential of vaccine-associated disease enhancement (VADE) following COVID-19 immunization.

       Here an attempt has been made to present the report of two patients admitted with confirmed COVID-19 pneumonia with a history of CoronaVac vaccination.

     The observations suggest that vaccination could act in boosting the inflammatory process and reveal the previously asymptomatic COVID-19 illness.

      More studies are needed to investigate the true incidence of VADE on vaccinated individuals as well as on how to differentiate between VADE and severe manifestations of COVID-19 that are unrelated to vaccination.

    Thus, an attempt is being made in this Booklet to discuss the importance of understanding VADE as it is essential for the decision making by the public, clinicians, and policymakers, needed for successful vaccination uptake along with relevant ILLUSTRATIONS for better understanding.

…Dr. H. K. Saboowala.

              M.B.(Bom) .M.R.S.H.(London)