Skin

Résumé du livre

CUTANEOUS TOXICOLOGY: AN OVERVIEW FROM THE UNDERSIDE. ANIMAL MODELS FOR THE STUDY OF SKIN IRRITANTS. THE SKIN OF DOMESTIC MAMMALS AS A MODEL FOR THE HUMAN SKIN, WITH SPECIAL REFERENCE TO THE DOMESTIC PIG. THE ROLE OF COLLAGEN IN PATHOPHYSIOLOGY OF THE SKIN; A MICROREVIEW. THE FINITE DOSE TECHNIQUE AS A VALID IN VITRO MODEL FOR THE STUDY OF PERCUTANEOUS ABSORPTION IN MAN. AN IMPROVED PROCEDURE FOR ASSAYING IRRITANTS: THE SCARIFICATION TEST. DETERMINATION OF PERCUTANEOUS ABSORPTION OF RADIOLABELED DRUGS IN VITRO AND IN VIVO BY HUMAN SKIN. FACTORS AFFECTING THE PERMEABILITY OF SKIN: THE RELATION BETWEEN IN VIVO AND IN VITRO OBSERVATIONS. THE USE OF MIXTURES OF TOPICAL CORTICOSTEROIDS AS A MECHANISM FOR IMPROVING TOTAL DRUG BIOAVAILABILITY: A PRELIMINARY REPORT. DESIGN OF CHEMICAL STRUCTURE FOR OPTIMAL DERMAL DELIVERY. HYDRATION AND PERCUTANEOUS ABSORPTION. FACTORS INFLUENCING THE PERCUTANEOUS ABSORPTION OF DRUGS. SOME PHYSICAL CHEMICAL FACTORS INFLUENCING PERCUTANEOUS ABSORPTION FROM DERMATOLOGICALS. PERMEABILITY OF SKIN: A REVIEW OF MAJOR CONCEPTS. HOUSWIVES SKIN AND HAZARDS OF DETERGENTS. GENTAMYCIN SERUM LEVELS IN A PATIENT WITH SEVERE SKIN DAMAGE. EXPLORATORY SKIN PENETRATION FINDINGS RELATING TO THE USE OF LEAD ACETATE HAIR DYES; HAIR AS A TEST TISSUE FOR MONITORING UPTAKE OF SYSTEMIC LEAD.