Secondary Surfactant Dysfunction and Deficiency

Résumé du livre

"Based on literature in Adult Respiratory Distress Syndrome in humans and evidence of surfactant activation in vitro and vivo, and our clinical observations of secondary respiratory decompensation in premature infants recovering from RDS, a study was designed to look at the possibility of benefit from secondary surfactant administration in premature infants with secondary decompensation after recovery from respiratory distress syndrom (RDS). A prospective pilot study was performed to study the effects of secondary surfactant administration on oxygenation, ventilation and pulmonary function of neonates who had respiratory decompensation after recovery from RDS. A secondary data analysis was performed looking at pulmonary function related to ventilatory efficiency index (VEI), modified ventilatory index (MVI) and respiratory severity score.