Anti-nematode Activity of Sixteen Compounds Against Trichinella Spiralis in Mice
Auteur : Johari Surin
Date de publication : 1995
Éditeur : Non disponible
Nombre de pages : Non disponible
Résumé du livre
The benzothiazoles (CGP21306, CGP20376, CGP21833 and CGP24588A) also indicated some anti-nematode activity together with 35vr, an imidazopyridine, but not as marked as the benzimidazole group. However, theorganic arsenical compounds (Mel Ga and Mel Ni) showed little activity and this was at a rather highly toxic level. The prospects of using the Trichinella-mouse model as a primary screen to test for potential macrofilaricides are discussed.