Recombinant Human Erythropoietin and Iron Supplementation in the Treatment of Anemia of Prematurity

Résumé du livre

Approximately 2500 [mu]g of a 57Fe-polymaltose complex orally, and 90 [mu]g of a saccharated 58Fe intravenously on the fourth day of the study. In addition, infants in groups 2 (n--10) and 3 (n--10) received approximately 850 U/kg of r-HuEpo 6 times at 3-day intervals. Infants in group 3 received saccharated iron at 1.95 mg/kg per day intravenously during the study. Means for erythrocyte incorporation of the dose of 57Fe label 14 days after dosing were not statistically different among the three groups (2.08 ± 1.18 % for group 1, 3.27 ± 1.97 % for group 2, and 2.89 ± 1.17 % for group 3). Means for erythrocyte incorporation of the dose of 58Fe label 14 days after dosing were not statistically different (33.59 ± 16.46 % for group 1, 37.32 ± 13.85 % for group 2, and 37.37 ± 20.52 % for group 3) among the three groups, either.