CELLULAR AND MOLECULAR EVENTS INVOLVED IN THE INITIATION OF THE IMMUNE RESPONSE TO PROTEUS MORGANII (CELLULAR EVENTS).

Résumé du livre

Because the secondary response is so restricted, we wanted to understand how this immune response is initiated. The first portion of this thesis characterizes the onset of the response to PC(PM). The principle observation discussed in Chapter One is that antibodies derived from the primary immune response have the same pattern of mutations seen in the secondary immune response. Moreover, antibodies lacking all but one of these mutations do not appear to be reactive with PC(PM). This observation results