Structure and Function of Intrinsically Disordered Proteins
Auteur : Peter Tompa, Alan Fersht
Date de publication : 2009-11-18
Éditeur : CRC Press
Nombre de pages : 359
Résumé du livre
The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure. Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug dev